Her role in the commercially successful sci-fi thriller Minority Report 2002 was followed by biographical portrayals of Myra Hindley in Longford 2006 , Deborah Curtis in Control 2007 , and Mary, Queen of Scots in Elizabeth: The Golden Age 2007.
She went straight from therapy into filming Synecdoche, New York 2008.
She had consolidated her reputation by following the Allen film up with work in indie features that showed that she was not only talented, but quite courageous as a performer.
She has received numerous accolades, including a British Academy Television Award, a British Independent Film Award, and a Golden Globe Award, and nominations for two Academy Awards, a Primetime Emmy Award, and a British Academy Film Award.
Was homeless for almost a year, sleeping at friends' houses or in bus shelters between the ages 13 - 14.